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Tuesday, May 25, 2010

Bacteria in soil enhance mood and intelligence

Exposure to specific bacteria in the environment, already believed to have antidepressant qualities, could increase learning behavior according to research presented today at the 110th General Meeting of the American Society for Microbiology in San Diego.

"Mycobacterium vaccae is a natural soil bacterium which people likely ingest or breath in when they spend time in nature," says Dorothy Matthews of The Sage Colleges in Troy, New York, who conducted the research with her colleague Susan Jenks.

Previous research studies on M. vaccae showed that heat-killed bacteria injected into mice stimulated growth of some neurons in the brain that resulted in increased levels of serotonin and decreased anxiety.

"Since serotonin plays a role in learning we wondered if live M. vaccae could improve learning in mice," says Matthews.

Matthews and Jenks fed live bacteria to mice and assessed their ability to navigate a maze compared to control mice that were not fed the bacteria.

"We found that mice that were fed live M. vaccae navigated the maze twice as fast and with less demonstrated anxiety behaviors as control mice," says Matthews.

In a second experiment the bacteria were removed from the diet of the experimental mice and they were retested. While the mice ran the maze slower than they did when they were ingesting the bacteria, on average they were still faster than the controls.

A final test was given to the mice after three weeks' rest. While the experimental mice continued to navigate the maze faster than the controls, the results were no longer statistically significant, suggesting the effect is temporary.

"This research suggests that M. vaccae may play a role in anxiety and learning in mammals," says Matthews. "It is interesting to speculate that creating learning environments in schools that include time in the outdoors where M. vaccae is present may decrease anxiety and improve the ability to learn new tasks."

Provided by American Society for Microbiology

Sunday, April 18, 2010

Brain implant- recorder or controller?

A brain-recording device that melts into place
April 18, 2010

Neural electrode array wrapped onto a model of the brain. The wrapping process occurs spontaneously, driven by dissolution of a thin, supporting base of silk. Credit: Please credit C. Conway and J. Rogers, Beckman Institute
Scientists have developed a brain implant that essentially melts into place, snugly fitting to the brain's surface. The technology could pave the way for better devices to monitor and control seizures, and to transmit signals from the brain past damaged parts of the spinal "These implants have the potential to maximize the contact between electrodes and brain tissue, while minimizing damage to the brain. They could provide a platform for a range of devices with applications in epilepsy, spinal cord injuries and other neurological disorders," said Walter Koroshetz, M.D., deputy director of the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
The study, published in Nature Materials, shows that the ultrathin flexible implants, made partly from silk, can record brain activity more faithfully than thicker implants embedded with similar electronics.
The simplest devices for recording from the brain are needle-like electrodes that can penetrate deep into brain tissue. More state-of-the-art devices, called micro-electrode arrays, consist of dozens of semi-flexible wire electrodes, usually fixed to rigid silicon grids that do not conform to the brain's shape.
In people with epilepsy, the arrays could be used to detect when seizures first begin, and deliver pulses to shut the seizures down. In people with spinal cord injuries, the technology has promise for reading complex signals in the brain that direct movement, and routing those signals to healthy muscles or prosthetic devices.
"The focus of our study was to make ultrathin arrays that conform to the complex shape of the brain, and limit the amount of tissue damage and inflammation," said Brian Litt, M.D., an author on the study and an associate professor of neurology at the University of Pennsylvania School of Medicine in Philadelphia. The silk-based implants developed by Dr. Litt and his colleagues can hug the brain like shrink wrap, collapsing into its grooves and stretching over its rounded surfaces.
The implants contain metal electrodes that are 500 microns thick, or about five times the thickness of a human hair. The absence of sharp electrodes and rigid surfaces should improve safety, with less damage to brain tissue. Also, the implants' ability to mold to the brain's surface could provide better stability; the brain sometimes shifts in the skull and the implant could move with it. Finally, by spreading across the brain, the implants have the potential to capture the activity of large networks of brain cells, Dr. Litt said.
Besides its flexibility, silk was chosen as the base material because it is durable enough to undergo patterning of thin metal traces for electrodes and other electronics. It can also be engineered to avoid inflammatory reactions, and to dissolve at controlled time points, from almost immediately after implantation to years later. The electrode arrays can be printed onto layers of polyimide (a type of plastic) and silk, which can then be positioned on the brain.
To make and test the silk-based implants, Dr. Litt collaborated with scientists at the University of Illinois in Urbana-Champaign and at Tufts University outside Boston. John Rogers, Ph.D., a professor of materials science and engineering at the University of Illinois, invented the flexible electronics. David Kaplan, Ph.D., and Fiorenzo Omenetto, Ph.D., professors of biomedical engineering at Tufts, engineered the tissue-compatible silk. Dr. Litt used the electronics and silk technology to design the implants, which were fabricated at the University of Illinois.
Recently, the team described a flexible silicon device for recording from the heart and detecting an abnormal heartbeat.
In the current study, the researchers approached the design of a brain implant by first optimizing the mechanics of silk films and their ability to hug the brain. They tested electrode arrays of varying thickness on complex objects, brain models and ultimately in the brains of living, anesthetized animals.
The arrays consisted of 30 electrodes in a 5x6 pattern on an ultrathin layer of polyimide - with or without a silk base. These experiments led to the development of an array with a mesh base of polyimide and silk that dissolves once it makes contact with the brain - so that the array ends up tightly hugging the brain.
Next, they tested the ability of these implants to record the animals' brain activity. By recording signals from the brain's visual center in response to visual stimulation, they found that the ultrathin polyimide-silk arrays captured more robust signals compared to thicker implants.
In the future, the researchers hope to design implants that are more densely packed with electrodes to achieve higher resolution recordings.
"It may also be possible to compress the silk-based implants and deliver them to the brain, through a catheter, in forms that are instrumented with a range of high performance, active electronic components," Dr. Rogers said.

Tuesday, March 30, 2010

Magnetic morality

Recent research has found that moral judgement is governed by an area of the brain just above the right ear. This can be 'turned off' by applying a magnet to the head in this area.

Turning off someone's moral compass is as easy as holding a magnet up to their head, new research from the Massachusetts Institute of Technology suggests.

Would this effect result from the field generated by a hairdryer in a salon? Or the smaller field from a phone?? Now there's a scary prospect.

Rather than judging people based on their actions, most people tend to judge based on the intent of those actions, too.

If a man trips his girlfriend on the sidewalk, for example, we determine if he is morally wrong based on whether it was by accident or on purpose.

But when a small area of the brain just above the right ear, called the right temporo-parietal junction, is disabled, we lose that ability entirely.

Instead, we judge the morality of an action based solely on its outcome. In this case, whether the girlfriend was hurt. If she came out of the trip unharmed, then the boyfriend was, morally speaking, in the clear regardless of whether he meant to injure her.

In the research project, led by Liane Young at MIT, people were asked to evaluate different scenarios like the one above and grade the morality of each person in question. Then a magnet was applied to the outside of their head just above the temporo-parietal junction, disabling the subject's ability to interpret intent.

The results astounded the researchers.

"Subjects were asked to judge how permissible it is for someone to let his girlfriend walk across a bridge he knows to be unsafe, even if she ends up making it across safely," said Anne Trafton, a spokeswoman at MIT.

"In such cases, a judgment based solely on the outcome would hold the perpetrator morally blameless, even though it appears he intended to do harm."

“You think of morality as being a really high-level behaviour,” she continued. “To be able to apply [a magnetic field] to a specific brain region and change people’s moral judgments is really astonishing.” Next, researchers want to examine perceptions of luck in moral judgment. A drunk driver, for example, may or may not kill someone as a result of their actions and whether they do is largely considered to be up to luck.

But the unlucky driver tends to be judged "more morally blameworthy,"

researchers suggest, even though both drivers did the same thing.

Young now hopes to discover if disabling the same part of the brain that determines intent has any effect on peoples' perceptions of luck.









Environment

Monday, March 01, 2010

I'm back, after more than a year inactive on this blog

Time to get doing again. I have recently uploaded the latest version of 'Eland Dances' on Authonomy.com. There are quite a few other aspiring writers, together with some published authors, who frequent the site.
The carrot is the long-shot possibility of some browsing agent or editor noticing your work and perhaps signing a contract. There is the even more unlikely possibility of Harper Collins, who run the site, liking something they see. The top five books in any given month get a review by Harper Collins editors.
Oh yes, everyone reads and 'backs' work they like. Each backing earns points, and these accumulate. The top five have each been backed by at least 1,200 others. After 2 weeks, mine has been backed by 97.
I don't expect to reach the top rating, but have had feedback from some, either praise or minor critique. Essentially if someone just plain doesn't like your stuff, you don't hear of it, because they simply pass over to something else.

Monday, January 05, 2009

New Year, ash borer

Today is my eldest daughters birthday. Everyone is partied out, like most years. This year we are going to have to celebrate her half-birthday instead, six months from now.
Back at the ranch meanwhile, firewood seems a bit harder to come by than in past years. Also wood pellets are sold out everywhere. A supplier has gone out of business, which is an opportunity for someone. Must be a big market, with all the pellet stoves in every hardware store lately. Surely the emerald ash borer situation makes this a good time to go into pellet production. Lots of ash available, and the heat and pressure of the pellet production process would kill all parasites. Perhaps Government regulation means a five year study before any such use of suspect wood.

Monday, December 22, 2008

Eland Dance

Eland Dance will be the title of the book.
Here is a synopsis of the novel
Peter Fitt is forced to face the realities of the Sixties in Central Africa. In the Congo, Zambia, and Zimbabwe greed and corruption fuel the growing turmoil. “Make Love not War” and “Peace and Love” are mantras often spoken, but rarely practised. Major forces are self-interest and each individual’s ideology. Red Communists, the Green agrarian Revolution, and the pervasive White Man’s way all have their partisans.
Old African beliefs about healing medicine and spirit powers come to the fore. A medicinal concoction should have three major parts, red, green, and white, to be fully effective, he learns.
Pete identifies with the spiritual herbivores of the world, the eland in San tradition, or unicorn in European mythology, against the predators, the exploiters, the lions. He is a defender, not an aggressor.
He helps with a development project in Zambia. In this he uses a Soviet aeroplane to transport fish to a lake straddling the southern border. The Russians take this opportunity to supply arms to the Rhodesian regime. While they claim to be peace lovers, in fact the Communists try to escalate the civil war, in order to assist their cadres into positions of power in the future Zimbabwe. Shit rises to the top when stirred. Thus they supply arms to both sides.
Pete shoots his girlfriend’s brother when he tries to prevent a gunfight between now well armed Rhodesian and Zimbabwean forces. Pete realises his culpability in this and other events. He can’t stop the war, or corruption and selfish power seeking, he can only look around for opportunities to assist others against these, and to influence the outcome of the war.
He helps to expose a Revolutionary, Bad Boy, who illicitly sells arms and ivory. This man is forced to go into Rhodesia on active service, which he has avoided. He is captured and jailed. Pete meets Marjorie’s mother and brother, and must try to explain and apologise
Later, Pete realises that those sitting out the war in captivity may become a large part of any new regime, while idealists who continue to fight on the front lines suffer high mortality. He helps with an amnesty/surrender deal between the Rhodesians and the Freedom Fighters. Pete is able to persuade some leaders that this is a good idea
Pete meets his spiritual other half, a one horned eland he had rescued from a fire years before, and is reunited with Marjorie. Despite the intervention of Bad Boy, the amnesty is a success.

swaz: Facebook

Have to learn some HTML, I think,since I have been having difficulty posting links.

swaz: Facebook

swaz: Facebook

Trying a different Template

I wanted to put in a link to my writing blog, and had so much difficulty that I have changed the template,and I think have now added the link in the sidebar.

Faceboook

I have started a Facebook page, and so far have three Fans. Also I now have a synopsis of the novel (Eland Dance) there and posted on my Writing Blog, which is
swazz7C.
All this takes time, but right now I am snowed in anyway. Minus about 12 or 15 out there and lots of blowing snow.
Sylvia has just brought me a nice young rat. She seems quite proud of herself. I am going to do a little disposal now, while she is elsewhere.

Thursday, December 18, 2008

December 08

Really winter now, and I cant find wood pellets for the stove. Luckily it is actually made to burn logs, not pellets, or there would be a real problem. They have pellet stoves on sale everywhere, but no fuel for them. I made a basket to hold pellets in the firebox last winter, and that works quite well. You have to load in fuel every few hours, with no screw feed, as there would be in a purpose built pellet burner.
Just writing what is on my mind right now, realised I really should keep this blog up to date.
Have just about finished my book, and tentatively given it a title, Eland Dances.
Soon I shall have to find a publisher-- a major undertaking.
I have a poem published (Surprise!) on Willows Wept Review, and have sent stories out to several magazines.

Sunday, March 09, 2008

negative ramblings

Snow lies heavy and long around here, big storm yesterday, highways and airports had big problems. March break, great timing.
Personally I worked yesterday 5am to 3pm, which came after working night shift 11pm to 7am for the past while. That leads to a definite fuzzy brain syndrome, never enough sleep.
Since the factory is going to close permanently this summer I have to grab money while its available, work any overtime offered.
Will get a pension as of May 31st, which will be my last day at Siemens. Not really enough to live on, but better than a slap with a wet fish.

Someone asked what i think of GM foods - well the idea in itself follows what nature does already (bacteria borrow genetic material, so do viruses). However scientists and marketers are not the best combination to ensure everything is properly safeguarded and thought out. Same pĂȘople who insist nuclear power is both safe and pollution free, as well as cheap. Sure it is safe, statistically a low accident rate. Problem is accidents can be very very damaging and with widespread consequences. Pollution similarly is low when looked at through a very narrow time frame- say the 3 year contract or tenure time of a plant manager - but lasts for 10s of thousands of years. Costs, again, are low if looked at over a short term, and use creative accounting that ignores government subsidies and repair and scrap disposal costs. We here in Ontario pay a surcharge on every electric bill for "debt disposal" which is to pay off the large debt incurred by the nuclear plants here.

Sorry, back to GM foods, which is supposed to be the subject. Plants can get disease resistance or extra protein content or whatever by adding genes from elsewhere, but obviously this is only a good thing when using the good ol narrow lens view.
Their modified genes spread outside the field they are planted in, regardless of Monsantos insistence otherwise. Short term demand for profit means testing for negative consequences is limited in scope and duration. Again, like nuclear, these consequences extend well beyond the tenure of their initiators.
So then, like in the nuclear industry --
Accidents do happen, when they do they spread very widely.
Costs are to others, not the producing companies, so dont count.
Consequences are very long lasting.

Monday, July 02, 2007

Summer

Just because of nothing in particular, here goes another update.
Seems my life goes on. Remarkable, actually, because I only recently looked up the official statistics on survival rates for the type and stage of cancer I had - They say that the 5 year survival rate from diagnosis with Stage 4 Oro-Pharyngeal Sarcoma (Throat cancer) is 30%.
Since I was diagnosed officially 0n 29th January 2004, it seems very probable that I will reach that 5 year mark. No symptoms of recurrence, though of course I.m constantly checking myself.
Yesterday i hauled my old bike out of the rubble heap and oiled it, fixed a puncture and pumped up the tyres. Today it.s ready to ride. Leaning against a cedar in the back there. Later, later.

Thursday, April 26, 2007

Ethanol and the Third World

Rising grain prices do not have to mean hunger in Africa. For years small farmers in Africa (and everywhere else) have been hobbled by the competition from subsidised 1st World grain farmers, and "Food Aid". Input costs in rural Africa ensured that maize could not be grown profitably as long as world market prices remained at $2something a bushel. Now perhaps there is actually incentive to grow food crops in countries like Zambia.
With the use of food grain as feedstock for Ethanol production, the demand for grain worldwide has jumped, and so have prices. Now people can potentially start out with very little, plant crops, and earn money.
Quite possibly the cycle of poverty and hunger can be broken, for many. For town dwellers of course, that will take longer. They will have to wait for the newly solvent farmers to need goods and services they can provide.
Perhaps this is the key to the different rates of development in Asian countries, as contrasted with Africa in general - rice has always been a profitable crop, while the crops usually planted in Africa have been subject to artificially low prices.

Thursday, March 29, 2007

spring

Long time no post, so its use it or-- . Spring is busy all around here, sun is shining and birds busy. I felt really miserable the past two days, snivelling in bed mostly, really down, despite the weather. Took lots of aspirin (dont like all the substitute things, the simplest medication seems to work) and some of that symptom- relief lemon stuff(almost as many ingredients as potato chips). Today woke up feeling almost rested, and able to breathe through my nose.
Last several months I have been busy, trying to get my novel into some kind of publishable form. Most difficult has been, and is, trying to see it through a strangers perspective, to read it as something fresh. Still dont know if it might actually might appeal to readers, and if so, which readers.Then the other thing is getting that first chapter and vital first page into something that will catch editors or publishers attention.
Another project has been getting together images and anecdotes about white animals, spurred by my encounters with the white squirrels that live in this area(Exeter Ontario). White buffalo, cattle, elephants, and horses have all been regarded as sacred by different cultures. Also other white animals such as the squirrels and peacocks certainly are very visually striking.

Saturday, October 07, 2006

newer photo

Since my photo in the profile is a fairly old one, it might be a good idea to post a newer image.

Saturday, September 09, 2006

September

So now we are past summer. Leaves on the ground after heavy rain early this morning, many already yellow. Before winter comes I have to decide whether to keep Billy goat Bob, or sell him. Unless I go for it, buy a nanny or two, and start seriously into goats, he is too much of a chore. Looking around, goats seem to be on quite a few farms in the area, so they must be a money-maker nowadays. OK then, I shall look out for a mate for him. Two goats wont be twice the hassle, just sorta his normal hassle plus a bit extra, I hope. That way, if it is too much, they can be sold as a going little herd, a breeding unit, and he is less likely to end up as stew.
My daughter and grandson have gone to Barbados for 3 weeks, they should have good weather at first, sunnny today and tomorrow, then some showers in the coming week. Must be on a beach right now. No comment .

Tuesday, July 18, 2006

Buy book

You can follow this link to buy the book
Support independent publishing: buy this book on Lulu.

Book now published

I have now become a published author, having self-published a book of short stories titled Heavy and Light Tales, available as of yesterday from Lulu.com.